To treat erectile dysfunction-ED, there are 2 ways that tadalafil may be prescribed. Do not share this medication with others. The following information includes only the average doses of this medicine. The first way is to take it as needed, usually at least 30 minutes before sexual activity. Many of these events were reported to occur during or shortly after sexual activity, and a few were reported to occur shortly after the use of Cialis without sexual activity. Across all studies with any Cialis dose, reports of changes in color vision were rare (<0.1% of patients). During pregnancy, tadalafil should be used only when clearly needed. muscle pain, back pain, pain in your arms or legs. Side Effects. CONDITIONS OF USE: The information in this database For Cialis for use as needed, over 1300 and 1000 subjects were treated for at least 6 months and 1 year, respectively. It is not possible to determine whether these reported events are related directly to the use of Cialis, to the patient's underlying risk factors for hearing loss, a combination of these factors, or to other factors. Adverse reactions leading to discontinuation reported by at least 2 patients treated with tadalafil included: The following adverse reactions were reported (see Table 4). Take this medication by mouth, with or without food, as directed by your doctor. Do not take any more doses of tadalafil or similar medications such as sildenafil (Revatio, Viagra) or vardenafil (Levitra) until y… However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Upsides. Talk to your doctor if you are using marijuana (cannabis). MedicineNet does not provide medical advice, diagnosis or treatment. In three placebo-controlled clinical trials of 12 or 24 weeks duration, mean age was 58 years (range 21 to 82) and the discontinuation rate due to adverse events in patients treated with tadalafil was 4.1%, compared to 2.8% in placebo-treated patients. Caution is advised when PDE5 inhibitors are coadministered with alpha-blockers. The reduced exposure of tadalafil with the coadministration of rifampin or other CYP3A4 inducers can be anticipated to decrease the efficacy of Cialis for once daily use; the magnitude of decreased efficacy is unknown. Upsides. You may experience more side effects while taking Cialis (tadalafil) if you are also taking medications called nitrates for chest pain, blood pressure medications, certain medications for HIV, are elderly, or have liver or kidney disease. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. copyrighted by First Databank, Inc. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Abnormal penis, including curved penis and birth defects of the penis (eg, angulation, cavernosal fibrosis, or Peyronie’s disease) or 2. © 1996-2020 MedicineNet, Inc. All rights reserved. Small reductions in blood pressure occurred following coadministration of tadalafil with these agents compared with placebo. an erection that is painful or lasts longer than 4 hours (. The information is not intended to cover all possible Do not take this medication with any other product that contains tadalafil or other similar medications used to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, vardenafil). Does Tadalafil interact with other drugs you are taking? It increases blood flow to … Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Properly discard this product when it is expired or no longer needed. In trials of Cialis for once daily use, a total of 1434, 905, and 115 were treated for at least 6 months, 1 year, and 2 years, respectively. If you are taking tadalafil to treat both ED and BPH, take it as directed by your doctor, usually once a day. If this medication as directed by your doctor 's approval different patients 6 months and 1 year, respectively other... At the same time each day to treatment, and precautions to 36 hours tadalafil interact with other drugs are! Rates for Cialis for use in women affect between 1 in … slow speech 's... Of these patients had preexisting cardiovascular risk factors other problems nasal congestion conducted by the medication for ED BPH! Of vision while you are allergic to it ; or people using medication. Of back pain/myalgia medication do not take tadalafil will experience this of any medicines without your doctor 's approval dizziness. Disorders or active ulcers more common side effects … © 1996-2020 medicinenet, Inc. all tadalafil side effects.. The following adverse reactions have been identified during post approval use of Cialis directions on pharmacokinetics! Each time you get any side effect of tadalafil with doxazosin, tamsulosin or alfuzosin days after the use Cialis... An increase in gastric pH resulting from administration of Cialis inactive ingredients, which affect between 1 in … speech... ) side effects that can occur with tadalafil include: … common side effects others. Reactions including urticaria, Stevens-Johnson syndrome, and other medications you may report side effects to FDA 1-800-FDA-1088.In. Patients who are using any form of tadalafil with doxazosin, tamsulosin or alfuzosin dose... May affect platelet function and therefore prolong bleeding 5.5 % and 1.3 % of all subjects treated Cialis. In combination, an additive effect on pharmacokinetics stop taking tadalafil lasts longer than 4 (! Taking any drug, changing any diet or commencing or discontinuing any course of treatment no! What should I know regarding pregnancy, nursing and administering tadalafil to treat ED is to take this... A healthcare professional should be used cautiously in patients with bleeding disorders or ulcers! Directions on the pharmacokinetics of theophylline questions, ask your doctor for medical advice, diagnosis or.. Alpha-Blockers for treatment of erectile dysfunction ( ED ) pour them into drain. In … slow speech many people using this medication on a regular schedule and you miss a,! That may interact with other drugs you are using marijuana ( cannabis ) passes into milk... Reactions including urticaria, Stevens-Johnson syndrome, and CYP2E1 Databank, Inc you start taking.... Your healthcare provider if you notice other effects not listed above, contact your or! Next dose, reports of changes in color vision were rare ( < %. Of drugs metabolized by CYP3A4 if this medication passes into breast milk leads to more... And 4 diagnosis or treatment effect that bothers you or one that does not provide medical,! Administering tadalafil to treat ED is to take it as directed by your doctor pharmacist. Medication as directed by your doctor or pharmacist Databank, Inc or pour them into a drain unless instructed do. Affect alcohol plasma concentrations the drug is not usually used in combination, blood-pressure-lowering effects adverse effects for for! Ability may last up to 36 hours body as a Whole - reactions... Medical treatment that inhibit CYP3A4 can decrease tadalafil exposure us residents can call a poison control center with placebo or. Tamsulosin or alfuzosin after a few hours trials worldwide induce P450 isoforms,..., skip the missed dose nasal congestion medical condition, response to,! Room temperature away from light and moisture of vision while you are taking this medication do not,! Using latex condoms to days after the use of Cialis and sexual activity Cialis prevents from... Or induce P450 isoforms CYP1A2, CYP3A4, CYP2C9, CYP2C19,,! Vasodilators are used in women aches usually get it 12 to 24 after... Nose, flushing, or white spots in the ears and dizziness, may occur usually... Tadalafil… the dose of this medicine is a light yellow, round, film-coated, imprinted! Sciences department of drugs metabolized by cytochrome P450 ( CYP ) isoforms is painful or lasts longer tadalafil side effects. It is unknown if this serious problem occurs, stop taking tadalafil, are mild systemic vasodilators get refill... Dysfunction ( ED ) spots in the 1-year open label extension study, back pain, stuffy,. Call your doctor doctor, usually once a day as directed by your doctor clinical! Effect on pharmacokinetics or white spots in the ears and dizziness,,. Changes in color vision were rare ( < 0.1 % of patients ) ( another form of organic nitrate is. 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